Here is only a small selection from the world-class collection of paintings:
* Cimabue (Maestà)
* Duccio (Maestà)
* Giotto (The Ognissanti Madonna, Badia Polyptych)
* Simone Martini (The Annunciation)
* Paolo Uccello (The Battle of San Romano)
* Piero della Francesca (Diptych of Duke Federico da Montefeltro and Duchess Battista Sforza of Urbino)
* Fra Filippo Lippi (Madonna with Child and Two Angels)
* Andrea del Verrocchio (The Baptism of Christ)
* Hugo van der Goes (The Portinari Triptych)
* Sandro Botticelli (Primavera, The Birth of Venus, The Adoration of the Magi and others)
* Leonardo da Vinci (The Annunciation, The Adoration of the Magi)
* Piero di Cosimo (Perseus liberating Andromeda)
* Albrecht Dürer (The Adoration of the Magi)
* Michelangelo (The Doni Tondo)
* Raphael (Madonna of the Goldfinch, Pope Leo X with Cardinals Giulio de' Medici and Luigi de' Rossi)
* Titian (Flora, Venus of Urbino)
* Parmigianino (The Madonna of the Long Neck)
* Caravaggio (Bacchus, The Sacrifice of Isaac, Medusa)
* Rembrandt Van Rijn (Self Portrait as a young man)